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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK4
All Species:
29.09
Human Site:
S468
Identified Species:
49.23
UniProt:
Q13043
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13043
NP_006273.1
487
55630
S468
E
I
R
Q
K
Y
Q
S
K
R
Q
P
I
L
D
Chimpanzee
Pan troglodytes
XP_001153224
503
57116
S484
E
I
R
Q
K
Y
Q
S
K
R
Q
P
I
L
D
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
S468
E
I
R
Q
K
Y
Q
S
K
R
Q
P
I
L
D
Dog
Lupus familis
XP_534432
487
55507
S468
E
I
R
Q
K
Y
Q
S
K
R
Q
P
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI11
487
55523
S468
E
I
R
Q
K
Y
R
S
K
R
Q
P
I
L
D
Rat
Rattus norvegicus
O54748
491
56103
A472
E
L
H
Q
R
Y
S
A
K
R
Q
P
I
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518508
281
31761
D274
E
A
Q
H
R
E
V
D
Q
D
D
E
E
N
S
Chicken
Gallus gallus
Q5ZJK4
486
55318
S467
E
I
R
Q
K
Y
Q
S
K
R
Q
P
I
L
D
Frog
Xenopus laevis
Q6PA14
485
55246
A466
E
I
H
H
K
Y
Q
A
K
R
Q
P
I
L
E
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
A473
E
L
R
Q
R
Y
T
A
K
R
Q
P
I
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
A643
Q
L
N
K
K
Y
N
A
K
R
Q
P
I
V
D
Honey Bee
Apis mellifera
XP_393691
465
52970
T457
P
I
L
D
A
M
D
T
K
R
K
R
Q
Q
N
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
T481
E
L
Q
R
R
Y
K
T
K
R
Q
P
I
L
D
Sea Urchin
Strong. purpuratus
XP_781787
488
55060
E469
E
L
R
K
R
Y
Q
E
K
R
R
P
I
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
99.3
97.3
N.A.
97.3
78
N.A.
55.8
92.1
76.5
77
N.A.
45.4
62.4
52.3
64.9
Protein Similarity:
100
95.8
99.7
98.9
N.A.
98.5
89.6
N.A.
57.2
96.5
86.8
87.4
N.A.
58.5
77.8
68.4
79.1
P-Site Identity:
100
100
100
100
N.A.
93.3
66.6
N.A.
6.6
100
73.3
73.3
N.A.
53.3
20
60
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
26.6
100
86.6
93.3
N.A.
86.6
40
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
29
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
8
0
8
8
0
0
0
72
% D
% Glu:
86
0
0
0
0
8
0
8
0
0
0
8
8
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
58
0
0
0
0
0
0
0
0
0
0
86
8
0
% I
% Lys:
0
0
0
15
58
0
8
0
93
0
8
0
0
0
0
% K
% Leu:
0
36
8
0
0
0
0
0
0
0
0
0
0
72
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
86
0
0
0
% P
% Gln:
8
0
15
58
0
0
50
0
8
0
79
0
8
8
0
% Q
% Arg:
0
0
58
8
36
0
8
0
0
93
8
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
43
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
8
15
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _